P0300 Random/Multiple-Cylinder Misfire: Meaning and Tests

The controller detected crankshaft-speed variation consistent with combustion loss across more than one cylinder.
Understand what a diagnostic trouble code monitors, what it does not prove, and which tests come next.

The controller detected crankshaft-speed variation consistent with combustion loss across more than one cylinder.
The controller reached a calibrated positive fuel correction because feedback indicated a lean condition on bank 1.

The catalyst monitor judged oxygen-storage performance below its calibrated threshold; the code does not prove the converter is the first failed part.
The evaporative monitor could not create or hold the expected vacuum or pressure, or it detected flow consistent with a large leak.
Warm-up behavior did not match the calibrated time and load model, commonly because measured coolant temperature rises too slowly.

A control module measured supply voltage below its calibrated threshold for the required time.
The controller detected an electrical or performance fault in the bank 1 sensor 1 heater circuit.
The EVAP monitor detected leakage smaller than a large-leak threshold, which makes test setup and stable sealing especially important.
Another module reported that expected communication with the engine or powertrain controller was absent.

A chassis controller detected a left-front wheel-speed circuit or signal fault; code wording varies by manufacturer.